More Articles
Donor giving plasma

CSL Plasma in Columbus, Ohio

First stop is the check-in desk. New donors are asked to present identification and complete screening and paperwork before heading to a donor bed, and returning donors move through a shorter screening. CSL describes the first visit as a longer appointment because of these safety checks, then subsequent visits are quicker.

CSL Plasma is a plasma donation provider that compensates donors on a reloadable prepaid card after each completed donation. Donors must meet the company’s eligibility and health-screening requirements and bring required documents such as a government-issued photo ID, proof of Social Security, and proof of current address. The company operates as part of the CSL Group, which includes CSL Behring, and publishes center-specific details on each location’s page rather than one-size-fits-all policies.

In Columbus, CSL Plasma runs two active centers with different schedules. The High Street center lists extended weekday hours and is also open on weekends. The Northland Plaza Drive center lists the same weekday hours, with a shorter Saturday and closed on Sunday. Both locations indicate they are taking new donors and offer free parking. If you have a preferred side of town or need an early morning slot, compare the two schedules and choose the one that fits.

  • Addresses: 2650 N. High Street, Columbus, OH 43202; 2617 Northland Plaza Dr, Columbus, OH 43231
  • Phones: High Street 614-267-4982; Northland Plaza 614-568-2205
  • Hours: High Street Mon–Fri 6 am–7 pm, Sat–Sun 7 am–3 pm; Northland Plaza Mon–Fri 6 am–7 pm, Sat 7 am–3 pm, Sun closed
  • Donor status: Taking new donors at both centers
  • Parking: Free parking
  • Payment: donor compensation loaded to a reloadable prepaid card; amounts and promotions vary by center
  • What to bring for first-time registration: government-issued photo ID, proof of Social Security, and proof of current address

If you are looking for a paid plasma donation option on the N. High Street corridor or near Northland with early weekday openings, CSL Plasma’s two Columbus centers publish their hours and intake status so you can plan a visit that matches your schedule.

Published: September 9, 2026 · Reviewed by the Whats Up Columbus editorial team