Blood & Plasma Donation Centers in Columbus, Ohio

Ready to roll up a sleeve for a whole blood appointment or to donate source plasma for medicines? This page keeps it simple. It lists every blood bank and plasma donation center tracked in our Health & Medical directory for Columbus so you can pick a nearby site and get your visit scheduled.

You’ll see both nonprofit blood donation options and commercial plasma centers. Blood donations support hospital needs such as surgeries and trauma care. Source plasma donations are used to manufacture therapies, and many plasma centers compensate donors for their time. Policies, ID requirements, and appointment systems vary by operator. Use the links below to reach each provider’s own page for current details.

If you’re new to donating, consider what matters most for your trip: location, appointment availability, and the type of donation you plan to make. The entries below call out one factual detail for quick orientation, then you can click through to confirm hours, eligibility, and what to bring.

• American Red Cross Of Greater Columbus: Operates the Carriage Place Blood Donation Center at 4820 Sawmill Road for scheduled blood and platelet appointments.
• Bio-Blood Components: Source plasma donation center on North High Street.
• Biomat USA: Grifols-operated plasma collection center at 3840 E Main Street in Whitehall.
• CSL Plasma: Center at 2650 N High Street.
• Octapharma Plasma: Operates two Columbus centers at 3467 Cleveland Ave and 83B Great Southern Blvd.
• Talecris Plasma Resources: Grifols-run plasma donation center at 3469 Great Western Blvd.

To narrow quickly, decide between a community blood donation and compensated plasma donation, then choose the location closest to your routine for the easiest follow-up visits.

Published: September 9, 2026 · Reviewed by the Whats Up Columbus editorial team